Reverse Diastolic Intrarenal Flow Due to Calcineurin Inhibitor (CNI) Toxicity
نویسندگان
چکیده
منابع مشابه
Calcineurin inhibitor toxicity in a renal transplant recipient
A 40-year-old Caucasian male who suffered end-stage renal disease due to unknown cause received a living-related renal allograft on 28 July 2008. Rabbit anti-thymocyte globulin was utilized for immediate post-transplant immunosuppressive induction, followed by maintenance immunosuppression with tacrolimus, mycophenolate mofetil and prednisone. Metoprolol was also administered for hypertension. ...
متن کاملIntrarenal vascular resistance parameters in kidney transplant patients receiving calcineurin inhibitor-based or sirolimus-based regimens.
BACKGROUND Use of a calcineurin inhibitor (CNI) immunosuppressant following kidney transplantation is associated with development of vasomotor nephrotoxicity. This study was undertaken to evaluate and compare the influences of CNI-based and CNI-free immunosuppressant regimens on two intrarenal vascular resistance parameters, the resistive index (RI) and the pulsatility index (PI), in renal tran...
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Propanone is a volatile liquid that can be absorbed by ingestion, inhalation, dermal and is distributed throughout the body. In this study, a fatal case involving acetone poisoning, who was worked in the Red Crescent Medical Center is presented. The deceased was found four hours after death. He was a 25-year-old male nurse and not married. There are the history of smoking since four years ago, ...
متن کاملCalcineurin inhibitor nephrotoxicity.
The use of the calcineurin inhibitors cyclosporine and tacrolimus led to major advances in the field of transplantation, with excellent short-term outcome. However, the chronic nephrotoxicity of these drugs is the Achilles' heel of current immunosuppressive regimens. In this review, the authors summarize the clinical features and histologic appearance of both acute and chronic calcineurin inhib...
متن کاملLate calcineurin inhibitor withdrawal prevents progressive left ventricular diastolic dysfunction in renal transplant recipients.
BACKGROUND Calcineurin inhibitor (CNI)-based therapy is associated with adverse cardiovascular effects. We examined the effects of late CNI or mycophenolate mofetil (MMF) withdrawal on echocardiographic parameters. METHODS This study was conducted as a substudy of a randomized trial in stable renal transplant recipients who were on a triple CNI-based regimen with prednisone and MMF that evalu...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2006
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2006.01381.x